A robust optimization model for multi-objective blood supply chain network considering scenario analysis under uncertainty: a multi-objective approach.

Annually, different regions of the world are affected by natural disasters such as floods and earthquakes, resulting in significant loss of lives and financial resources. These events necessitate rescue operations, including the provision and distribution of relief items like food and clothing. One of the most critical challenges in such crises is meeting the blood requirement, as an efficient and reliable blood supply chain is indispensable. The perishable nature of blood precludes the establishment of a reserve stock, making it essential to minimize shortages through effective approaches and designs. In this study, we develop a mathematical programming model to optimize supply chains in post-crisis scenarios using multiple objectives. Presented model allocates blood to various demand facilities based on their quantity and location, considering potential situations. We employ real data from a case study in Iran and a robust optimization approach to address the issue. The study identifies blood donation centers and medical facilities, as well as the number and locations of new facilities needed. We also conduct scenario analysis to enhance the realism of presented approach. Presented research demonstrates that with proper management, crises of this nature can be handled with minimal expense and deficiency.

A deeply supervised adaptable neural network for diagnosis and classification of Alzheimer's severity using multitask feature extraction.

Alzheimer's disease is the most prevalent form of dementia, which is a gradual condition that begins with mild memory loss and progresses to difficulties communicating and responding to the environment. Recent advancements in neuroimaging techniques have resulted in large-scale multimodal neuroimaging data, leading to an increased interest in using deep learning for the early diagnosis and automated classification of Alzheimer's disease. This study uses machine learning (ML) methods to determine the severity level of Alzheimer's disease using MRI images, where the dataset consists of four levels of severity. A hybrid of 12 feature extraction methods is used to diagnose Alzheimer's disease severity, and six traditional machine learning methods are applied, including decision tree, K-nearest neighbor, linear discrimination analysis, Naïve Bayes, support vector machine, and ensemble learning methods. During training, optimization is performed to obtain the best solution for each classifier. Additionally, a CNN model is trained using a machine learning system algorithm to identify specific patterns. The accuracy of the Naïve Bayes, Support Vector Machines, K-nearest neighbor, Linear discrimination classifier, Decision tree, Ensembled learning, and presented CNN architecture are 67.5%, 72.3%, 74.5%, 65.6%, 62.4%, 73.8% and, 95.3%, respectively. Based on the results, the presented CNN approach outperforms other traditional machine learning methods to find Alzheimer severity.

The performance of artificial intelligence language models in board-style dental knowledge assessment: A preliminary study on ChatGPT.

BACKGROUND: Although Chat Generative Pre-trained Transformer (ChatGPT) (OpenAI) may be an appealing educational resource for students, the chatbot responses can be subject to misinformation. This study was designed to evaluate the performance of ChatGPT on a board-style multiple-choice dental knowledge assessment to gauge its capacity to output accurate dental content and in turn the risk of misinformation associated with use of the chatbot as an educational resource by dental students. METHODS: ChatGPT3.5 and ChatGPT4 were asked questions obtained from 3 different sources: INBDE Bootcamp, ITDOnline, and a list of board-style questions provided by the Joint Commission on National Dental Examinations. Image-based questions were excluded, as ChatGPT only takes text-based inputs. The mean performance across 3 trials was reported for each model. RESULTS: ChatGPT3.5 and ChatGPT4 answered 61.3% and 76.9% of the questions correctly on average, respectively. A 2-tailed t test was used to compare 2 independent sample means, and a 2-tailed χ2 test was used to compare 2 sample proportions. A P value less than .05 was considered to be statistically significant. CONCLUSION: ChatGPT3.5 did not perform sufficiently well on the board-style knowledge assessment. ChatGPT4, however, displayed a competent ability to output accurate dental content. Future research should evaluate the proficiency of emerging models of ChatGPT in dentistry to assess its evolving role in dental education. PRACTICAL IMPLICATIONS: Although ChatGPT showed an impressive ability to output accurate dental content, our findings should encourage dental students to incorporate ChatGPT to supplement their existing learning program instead of using it as their primary learning resource.